Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 9/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651798 | 0.81 | ALDH1A1 (0.53) | HSD17B10PDE7ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL30388476 | 0.80 | HSD17B10 (0.64) | HSD17B10VCAM1PDE7APDE4BPDE4D | |
| SCHEMBL5024770 | 0.80 | HSD17B10 (0.64) | HSD17B10VCAM1PDE7APDE4BPDE4D | |
| SCHEMBL10911651 | 0.80 | ALDH1A1 (0.55) | HSD17B10PDE7APDE4BPDE4DPDE7B | |
| SCHEMBL11739688 | 0.80 | PDE7A (0.49) | HSD17B10PDE7APDE7BTXNRD1TXNRD3 | |
| SCHEMBL18247898 | 0.78 | ALDH1A1 (0.49) | HSD17B10PDE7APDE4BPDE4DPDE7B | |
| SCHEMBL19625104 | 0.77 | HSD17B10 (0.60) | HSD17B10VCAM1PDE7APDE4BPDE4D | |
| SCHEMBL927819 | 0.77 | HSD17B10 (0.60) | HSD17B10VCAM1PDE7APDE4BPDE4D | |
| SCHEMBL5024771 | 0.77 | HSD17B10 (0.60) | HSD17B10VCAM1PDE7APDE4BPDE4D | |
| SCHEMBL16295003 | 0.74 | ERN1 (0.53) | PDE7ATXNRD1TXNRD3TXNRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962450-B1 | Process for the preparation of perfluoalkylaryl sulfides | BAYER AG (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-6175042-B1 | A CHEMICAL INTERMEDIATE FOR AGROCHEMICALS, PHARMACEUTICALS, DYES, AND POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-16 | — | — | US | disclosed |
| EP-0962450-A1 | Process for the preparation of perfluoalkylaryl sulfides and perfluoroalkylaryl sulfides per se | Bayer Aktiengesellschaft (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0318704-B1 | 3-CYANO-4-PHENYL-PYRROLE DERIVATIVES | BAYER AG (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-5015757-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4960789-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0318704-A2 | 3-Cyano-4-phenyl-pyrrole derivatives | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |