Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 11/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011082 | 0.90 | STAT3 (0.43) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL7008719 | 0.89 | STAT3 (0.52) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL7014564 | 0.84 | CYP3A4 (0.46) | STAT3ALDH1A1HTTTOP1POLB | |
| SCHEMBL7007324 | 0.84 | STAT3 (0.42) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL7010691 | 0.83 | STAT3 (0.39) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL6576283 | 0.81 | TOP1 (0.43) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL7009143 | 0.81 | TOP1 (0.57) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL7006109 | 0.80 | TOP1 (0.41) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL6581471 | 0.80 | TOP2A (0.42) | STAT3ALDH1A1HTTTOP1KDM4E | |
| SCHEMBL7005300 | 0.78 | TOP1 (0.49) | STAT3ALDH1A1HTTTOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787720-B1 | PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KK (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-5910498-A | NOVEL COMPOUNDS HAVING REDUCED CYTOTOXICITY, PHOTOTOXICITY; TREATING BACTERIAL AND VIRAL INFECTIONS | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1999-06-08 | — | — | US | disclosed |