SCHEMBL700722

SCHEMBL700722

O=C(Cl)Oc1ccc2c(c1)Oc1cc(O)ccc1C21OC(=O)c2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.73
MAPT P10636 4/20 0.73
MEN1 O00255 4/20 0.73
KMT2A Q03164 4/20 0.73
TDP1 Q9NUW8 3/20 0.73
HTT P42858 2/20 0.73
HPGD P15428 2/20 0.73
RECQL P46063 2/20 0.73
BLM P54132 2/20 0.73
ACE2 Q9BYF1 2/20 0.73
CYP2C19 P33261 1/20 0.73
SMAD3 P84022 1/20 0.73
PRMT1 Q99873 1/20 0.73
LMNA P02545 3/20 0.70
ALDH1A1 P00352 3/20 0.70
USP2 O75604 2/20 0.70
CYP3A4 P08684 2/20 0.58
GSTP1 P09211 1/20 0.54
GPR55 Q9Y2T6 2/20 0.53
ALOX12 P18054 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174468 0.90 FTO (0.75) FTOMAPTMEN1KMT2ATDP1
SCHEMBL2285435 0.89 MAPT (0.89) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL11240448 0.88 FTO (0.89) FTOMAPTMEN1KMT2ATDP1
SCHEMBL6244972 0.88 FTO (0.69) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL28633518 0.88 FTO (0.94) FTOMAPTMEN1KMT2ATDP1
SCHEMBL1644447 0.88 MAPT (0.87) FTOMAPTMEN1KMT2ATDP1
SCHEMBL4663321 0.87 FTO (0.82) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL700723 0.87 FTO (0.87) FTOMAPTMEN1KMT2ATDP1
SCHEMBL1228363 0.87 FTO (0.70) FTOMAPTMEN1KMT2ATDP1
SCHEMBL21194989 0.87 FTO (0.70) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124756-B2 Method of preparing 5′-amino-linker oligonucleotides derivatives and analogous 5′-labeled-linker oligonucleotides therefrom POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2012-02-28 US claimed
US-20100093994-A1 REPARATION METHOD OF AN AMINO LINKER OLIGONUCLEOTIDES AND LABELED-LINKER OLIGONUCLEOTIDE THEREFROM POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2010-04-15 US claimed