SCHEMBL7007440

SCHEMBL7007440

Cc1ccc(Nc2ccccc2N(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.53
GAA P10253 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
HPGD P15428 5/20 0.48
KDM1A O60341 4/20 0.41
RAPGEF4 Q8WZA2 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.38
EGFR P00533 1/20 0.38
TP53 P04637 3/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HTT P42858 3/20 0.36
MITF O75030 1/20 0.36
CDC25B P30305 2/20 0.36
UBE2I P63279 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
UBA2 Q9UBT2 1/20 0.36
KDM4E B2RXH2 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7005567 0.92 MAPT (0.54) MAPTGAATDP1NPC1RAB9A
SCHEMBL7006256 0.92 MAPT (0.54) MAPTGAATDP1NPC1RAB9A
SCHEMBL7005122 0.89 MAPT (0.51) MAPTGAATDP1NPC1RAB9A
SCHEMBL7010069 0.88 MAPT (0.49) MAPTGAATDP1NPC1RAB9A
SCHEMBL11731265 0.81 MAPT (0.56) MAPTGAATDP1NPC1RAB9A
SCHEMBL3175953 0.81 MAPT (0.48) MAPTGAATDP1NPC1RAB9A
SCHEMBL30296910 0.81 MAPT (0.48) MAPTGAATDP1NPC1RAB9A
SCHEMBL17385557 0.80 MAPT (0.39) MAPTGAATDP1NPC1RAB9A
SCHEMBL5839725 0.79 NPSR1 (0.50) MAPTGAATDP1NPC1RAB9A
SCHEMBL7147096 0.78 TSHR (0.48) MAPTTDP1HPGDL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995786-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2003-01-08 EP disclosed
US-6208452-B1 HAS AN ION CONDUCTIVE LAYER OBTAINED BY CURING A COMPOSITION COMPRISING A BIPYRIDINIUM COMPOUND, A SPECIFIC AMINE COMPOUND AND A PRECURSOR COMPONENT OF A POLYMERIC SOLID ELECTROLYTE DISPOSED BETWEEN TWO ELECTRICALLY CONDUCTIVE SUBSTRATES NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-27 US disclosed
US-6203154-B1 MULTILAYER NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-20 US disclosed
EP-1041425-A1 ELECTROCHROMIC ELEMENT Nippon Mitsubishi Oil Corporation (JP) 2000-10-04 EP disclosed
EP-0995786-A1 Electrochromic device Nippon Mitsubishi Oil Corporation (JP) 2000-04-26 EP disclosed