Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007583 | 0.91 | TOP2A (0.55) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL7017683 | 0.90 | TOP2A (0.45) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL7498486 | 0.86 | PDE4D (0.34) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL7010007 | 0.86 | TOP2A (0.46) | TOP2ATOP2BKCNH2POLB | |
| SCHEMBL7012608 | 0.81 | TOP2A (0.43) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL8318407 | 0.81 | TOP2A (0.43) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL7502599 | 0.81 | TOP2A (0.44) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL7012229 | 0.80 | TOP2A (0.57) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL7012404 | 0.79 | TOP2A (0.51) | TOP2ATOP2BKCNH2KDM4EALDH1A1 | |
| SCHEMBL7009330 | 0.79 | TOP2A (0.55) | TOP2ATOP2BKCNH2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | claimed |