Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 3/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001592 | 0.90 | TOP2A (0.44) | TOP2ATOP2BKCNH2POLBKDM4E | |
| SCHEMBL7502021 | 0.89 | KCNH2 (0.40) | PDE4DTOP2ATOP2BKCNH2POLB | |
| SCHEMBL7007585 | 0.86 | TOP2A (0.44) | TOP2ATOP2BKCNH2POLBKDM4E | |
| SCHEMBL7494743 | 0.86 | KCNH2 (0.34) | PDE4DTOP2ATOP2BKCNH2POLB | |
| SCHEMBL12279579 | 0.84 | TOP2A (0.41) | TOP2ATOP2BKCNH2POLBKDM4E | |
| SCHEMBL12279915 | 0.80 | TOP2A (0.41) | TOP2ATOP2BKCNH2POLBKDM4E | |
| SCHEMBL12279774 | 0.80 | KCNH2 (0.40) | TOP2ATOP2BKCNH2POLBKDM4E | |
| SCHEMBL4992199 | 0.80 | TOP2A (0.44) | TOP2ATOP2BKCNH2POLBKDM4E | |
| SCHEMBL12280737 | 0.79 | KCNH2 (0.43) | TOP2ATOP2BKCNH2POLBKDM4E | |
| SCHEMBL12279903 | 0.79 | TOP2A (0.42) | TOP2ATOP2BKCNH2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882725-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-12-18 | — | — | EP | claimed |