Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.56 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472665 | 1.00 | TACR1 (0.56) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL7009113 | 0.93 | TACR1 (0.57) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL7075456 | 0.93 | TACR1 (0.57) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3473136 | 0.93 | TACR1 (0.53) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3473472 | 0.93 | TACR1 (0.53) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL6836873 | 0.91 | TACR1 (0.57) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3475829 | 0.91 | TACR1 (0.57) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL5457820 | 0.84 | TACR1 (0.70) | TACR1SCN5ASCN9ATACR3 | |
| SCHEMBL6836750 | 0.83 | TACR1 (0.58) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3475643 | 0.83 | TACR1 (0.58) | TACR1UBE2MDCUN1D1SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328516-A1 | NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | Boehringer Ingelheim Pharma KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032865-A1 | NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |