Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.57 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475829 | 1.00 | TACR1 (0.57) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3472665 | 0.91 | TACR1 (0.56) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL7007590 | 0.91 | TACR1 (0.56) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3473472 | 0.89 | TACR1 (0.53) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3473136 | 0.89 | TACR1 (0.53) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL3475643 | 0.89 | TACR1 (0.58) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL6836750 | 0.89 | TACR1 (0.58) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL7009113 | 0.88 | TACR1 (0.57) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL7075456 | 0.88 | TACR1 (0.57) | TACR1UBE2MDCUN1D1SCN5ASCN9A | |
| SCHEMBL5457820 | 0.86 | TACR1 (0.70) | TACR1SCN5ASCN9ATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747044-B2 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; ANTIULCER AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-06-08 | — | — | US | disclosed |
| EP-1328516-A1 | NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | Boehringer Ingelheim Pharma KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-20030100565-A1 | Method for the treatment or prevention of atopic dermatitis | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2003-05-29 | — | — | US | disclosed |
| EP-1295599-A1 | Method for the treatment of prevention of atopic dermatitis | Boehringer Ingelheim International GmbH (DE) | 2003-03-26 | — | — | EP | disclosed |
| US-20020147219-A1 | Neurokinin antagonists | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-10-10 | — | — | US | disclosed |
| WO-2002032865-A1 | NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147219-A1 | Neurokinin antagonists | TACR2, TACR1, TAC3 | TACR1 2/4885UBE2M 4412/4885DCUN1D1 1570/4885 |
| US-20030100565-A1 | Method for the treatment or prevention of atopic dermatitis | TACR1, BDKRB1, CPA3 | TACR1 1/4885UBE2M 4109/4885DCUN1D1 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.