Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202914 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMTPMTALDH1A1KDM4E | |
| SCHEMBL27287426 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMTPMTALDH1A1KDM4E | |
| SCHEMBL27974983 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2PKMTPMTALDH1A1KDM4E | |
| SCHEMBL1202939 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2PKMTPMTALDH1A1KDM4E | |
| SCHEMBL20396247 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2PKMTPMTPTPN1ALDH1A1 | |
| SCHEMBL27439512 | 0.79 | PTPN1 (0.44) | SMN1; SMN2TPMTPTPN1ALDH1A1KDM4E | |
| SCHEMBL7009937 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2PKMALDH1A1KDM4EPOLB | |
| SCHEMBL27565467 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMTPMTALDH1A1KDM4E | |
| SCHEMBL27640077 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMTPMTALDH1A1KDM4E | |
| SCHEMBL27722046 | 0.75 | MEN1 (0.44) | SMN1; SMN2TPMTPTPN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |