Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 5/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.49 |
| ▸ | TOP1 | P11387 | 7/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013056 | 0.92 | KDM4E (0.60) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL7011074 | 0.90 | KDM4E (0.58) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL6305606 | 0.85 | KDM4E (0.80) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL10739298 | 0.84 | KDM4E (0.79) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL312379 | 0.84 | KDM4E (0.76) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL7007104 | 0.84 | KDM4E (0.63) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL11187784 | 0.84 | KDM4E (0.68) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL11187466 | 0.84 | KDM4E (0.68) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| Water SCHEMBL10765060 | 0.83 | KDM4E (0.75) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL10743594 | 0.83 | KDM4E (0.77) | KDM4EHPGDHSD17B10ALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5889009-A | ADMINISTERING 1,7-DISUBSTITUTED-4-OX-3-(QUINOLINECARBOXYLIC ACID OR NAPHTHYRIDINECARBOXYLIC ACID) | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0614664-B1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5703081-A | CELL ADHESION INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5519024-A | CELL ADHESION INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0614664-A1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |