SCHEMBL7007803

SCHEMBL7007803

CN1CC=C(c2c[nH]c3ccc(C4=CCN5CCC[C@H]5C4)cc23)CC1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7007800 1.00 SLC6A4 (0.59) SLC6A4
SCHEMBL7007906 0.84 SLC6A4 (0.59) SLC6A4
SCHEMBL7007905 0.84 SLC6A4 (0.59) SLC6A4
SCHEMBL7002581 0.83 SLC6A4 (0.39) SLC6A4
SCHEMBL7001453 0.83 SLC6A4 (0.39) SLC6A4
SCHEMBL7001456 0.83 SLC6A4 (0.39) SLC6A4
SCHEMBL6999444 0.81 SLC6A4 (0.56) SLC6A4
SCHEMBL6999439 0.81 SLC6A4 (0.56) SLC6A4
SCHEMBL6995736 0.80 PIM1 (0.44) SLC6A4
SCHEMBL7001003 0.80 SLC6A4 (0.38) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1098896-B1 5-BICYCLOINDOLE COMPOUNDS NPS ALLELIX CORP (CA) 2003-06-25 EP claimed
EP-1098896-A1 5-BICYCLOINDOLE COMPOUNDS NPS Allelix Corp. (CA) 2001-05-16 EP claimed
WO-2000004019-A1 5-BICYCLOINDOLE COMPOUNDS ALLELIX BIOPHARMACEUTICALS INC. (CA) 2000-01-27 WO claimed
EP-1098896-B1 5-BICYCLOINDOLE COMPOUNDS NPS ALLELIX CORP (CA) 2003-06-25 EP disclosed
EP-1098896-A1 5-BICYCLOINDOLE COMPOUNDS NPS Allelix Corp. (CA) 2001-05-16 EP disclosed
WO-2000004019-A1 5-BICYCLOINDOLE COMPOUNDS ALLELIX BIOPHARMACEUTICALS INC. (CA) 2000-01-27 WO disclosed