Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354708 | 0.90 | EGFR (0.76) | ERBB2EGFR | |
| SCHEMBL4359057 | 0.88 | ERBB2 (0.79) | ERBB2EGFR | |
| SCHEMBL2202476 | 0.87 | ERBB2 (1.00) | ERBB2EGFR | |
| Hydrochloric Acid SCHEMBL7007221 | 0.86 | ERBB2 (0.98) | ERBB2EGFR | |
| SCHEMBL7010246 | 0.86 | ERBB2 (0.72) | ERBB2EGFR | |
| SCHEMBL7009047 | 0.85 | ERBB2 (0.91) | ERBB2EGFR | |
| SCHEMBL7005564 | 0.82 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL7005290 | 0.81 | ERBB2 (0.85) | ERBB2EGFR | |
| Hydrochloric Acid SCHEMBL7013332 | 0.81 | ERBB2 (0.98) | ERBB2EGFR | |
| Hydrochloric Acid SCHEMBL7901747 | 0.81 | ERBB2 (0.84) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912572-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2003-01-15 | — | — | EP | claimed |
| US-6207669-B1 | IN TREATMENT OF CANCER AND PSORIASIS | GLAXO WELLCOME INC. | 2001-03-27 | — | — | US | claimed |
| EP-0912572-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1999-05-06 | — | — | EP | claimed |
| WO-1998002437-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-01-22 | — | — | WO | claimed |
| EP-0912572-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2003-01-15 | — | — | EP | disclosed |
| US-6207669-B1 | IN TREATMENT OF CANCER AND PSORIASIS | GLAXO WELLCOME INC. | 2001-03-27 | — | — | US | disclosed |