Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357901 | 0.97 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL3966397 | 0.90 | TSHR (0.35) | TSHRLMNATHRB | |
| Bromide SCHEMBL6697844 | 0.90 | TSHR (0.35) | TSHRLMNATHRBDNM1 | |
| SCHEMBL3817363 | 0.90 | TSHR (0.41) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL3813741 | 0.90 | TSHR (0.35) | TSHRLMNATHRB | |
| SCHEMBL383130 | 0.90 | — | — | |
| SCHEMBL3818601 | 0.88 | TSHR (0.47) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL3820749 | 0.88 | TSHR (0.47) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL3233105 | 0.88 | TSHR (0.47) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL9350919 | 0.87 | TSHR (0.38) | TSHRLMNATHRBDNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107947-B1 | METHOD FOR PRODUCING CYANOVALERIC ACID OR ESTERS THEREOF | BASF AG (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-6346640-B1 | REACTION OF PENTENENITRILE WITH CARBON MONOXIDE AND HYDROXY COMPOUNDS IN THE PRESENCE OF CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-12 | — | — | US | disclosed |
| EP-0529698-B1 | Process for the preparation of alcohols | SHELL INT RESEARCH (NL) | 1996-10-16 | — | — | EP | disclosed |
| EP-0577204-B1 | Preparation of alkanedioic derivatives | SHELL INT RESEARCH (NL) | 1996-10-09 | — | — | EP | disclosed |
| EP-0495547-B1 | Carbonylation of olefins | SHELL INT RESEARCH (NL) | 1996-04-24 | — | — | EP | disclosed |
| US-5304674-A | Preparation of alkanedioic derivatives | SHELL OIL COMPANY (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0577204-A2 | Preparation of alkanedioic derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-01-05 | — | — | EP | disclosed |
| US-5214220-A | Hydrogenation of aldehydes, Group VIII metal compound, bidentate phosphine | SHELL OIL COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0529698-A2 | Process for the preparation of alcohols | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-03-03 | — | — | EP | disclosed |
| EP-0495547-A2 | Carbonylation of olefins | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-07-22 | — | — | EP | disclosed |