Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383130 | 0.94 | — | — | |
| SCHEMBL7008089 | 0.90 | TSHR (0.38) | TSHRLMNATHRB | |
| SCHEMBL9350919 | 0.90 | TSHR (0.38) | TSHRLMNATHRB | |
| SCHEMBL15656735 | 0.90 | TSHR (0.43) | TSHRLMNATHRB | |
| SCHEMBL15657330 | 0.90 | TSHR (0.43) | TSHRLMNATHRB | |
| SCHEMBL15660178 | 0.90 | — | — | |
| SCHEMBL5172031 | 0.90 | TSHR (0.43) | TSHRLMNATHRB | |
| SCHEMBL9494791 | 0.88 | — | — | |
| SCHEMBL29209993 | 0.88 | TSHR (0.41) | TSHRLMNATHRB | |
| Hydrochloric Acid SCHEMBL11571153 | 0.87 | TSHR (0.40) | TSHRLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1318362-C | One-step process for the preparation of 1, 3-diols | SHELL INT RESEARCH (NL) | 2007-05-30 | — | — | CN | claimed |
| CN-1635987-A | One step process for preparing a 1,3-diol | SHELL INT RESEARCH (NL) | 2005-07-06 | — | — | CN | claimed |
| EP-1268060-B1 | ONE STEP PROCESS FOR PREPARING A 1,3-DIOL | SHELL INT RESEARCH (NL) | 2004-05-12 | — | — | EP | claimed |
| US-6706656-B2 | PREPARING A HYDROFORMYLATION CATALYST BY REACTING A RUTHENIUM (0) COMPOUND WITH A DITERTIARY PHOSPHINE LIGAND, AND COMPLEXING THE RESULTING COMPLEX VIA A REDOX REACTION WITH A COBALT(0) CARBONYL COMPOUND | SHELL OIL COMPANY | 2004-03-16 | — | — | US | claimed |
| US-20030040647-A1 | One step process for preparing a 1,3-diol | SHELL OIL COMPANY | 2003-02-27 | — | — | US | claimed |
| EP-1268060-A2 | ONE STEP PROCESS FOR PREPARING A 1,3-DIOL | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2003-01-02 | — | — | EP | claimed |
| US-20020161251-A1 | One step process for preparing a 1,3-diol | KNIFTON JOHN FREDERICK (US) | 2002-10-31 | — | — | US | claimed |
| US-6469222-B2 | OXIRANE HYDROFORMYLATION CATALYST | SHELL OIL COMPANY | 2002-10-22 | — | — | US | claimed |
| US-20020111516-A1 | One Step Process for preparing a 1,3-diol | KNIFTON JOHN FREDERICK (US) | 2002-08-15 | — | — | US | claimed |
| US-20020004617-A1 | One step process for preparing A 1,3-DIOL | SHELL OIL COMPANY | 2002-01-10 | — | — | US | claimed |
| WO-2001072675-A2 | ONE STEP PROCESS FOR PREPARING A 1,3-DIOL | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2001-10-04 | — | — | WO | claimed |
| CN-100522905-C | Synthesis of aliphatic 1,3-diols utilizing reduced ligand concentration and water extraction | SHELL INT RESEARCH (NL) | 2009-08-05 | — | — | CN | disclosed |
| US-7538061-B2 | One-step production of 1,3-propanediol from ethylene oxide and syngas with a cobalt-iron catalyst | SHELL OIL COMPANY (US) | 2009-05-26 | — | — | US | disclosed |
| CN-100406121-C | One-step production of 1,3-propanediol from ethylene oxide and syngds with cobalt-iron catalyst | SHELL INTERNAT RES MAATSHAPPIJ (NL) | 2008-07-30 | — | — | CN | disclosed |
| CN-1318362-C | One-step process for the preparation of 1, 3-diols | SHELL INT RESEARCH (NL) | 2007-05-30 | — | — | CN | disclosed |
| US-6469222-B2 | OXIRANE HYDROFORMYLATION CATALYST | SHELL OIL COMPANY | 2002-10-22 | — | — | US | disclosed |
| US-6468940-B1 | COMPLEX OF OXIDIZED RUTHINIUM METAL THAT IS LIGATED BY A TERTIARY DIPHOSPHINE LIGAND AND A COBALT COMPOUND WHICH IS NOT LIGATED BY A DIPHOSPHINE LIGAND; 1,3-PROPANEDIOL FROM HYDROFORMYLATION OF ETHYLENE OXIDE WITH SYNTHESIS GAS | SHELL OIL COMPANY | 2002-10-22 | — | — | US | disclosed |
| US-20020111516-A1 | One Step Process for preparing a 1,3-diol | KNIFTON JOHN FREDERICK (US) | 2002-08-15 | — | — | US | disclosed |
| US-20020004617-A1 | One step process for preparing A 1,3-DIOL | SHELL OIL COMPANY | 2002-01-10 | — | — | US | disclosed |
| WO-2001072675-A2 | ONE STEP PROCESS FOR PREPARING A 1,3-DIOL | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2001-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040647-A1 | One step process for preparing a 1,3-diol | OXGR1, OXER1, ADH1A | TSHR 3493/4885LMNA 4571/4885THRB 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.