Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944930 | 0.90 | ADRB2 (0.56) | ADRB2KCNH2TOP2ATOP2BGSK3B | |
| SCHEMBL7011678 | 0.90 | ADRB2 (0.56) | ADRB2KCNH2TOP2ATOP2BGSK3B | |
| SCHEMBL13355583 | 0.90 | ADRB2 (0.59) | ADRB2KCNH2TOP2ATOP2BGSK3B | |
| SCHEMBL7599453 | 0.88 | ADRB2 (0.65) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL4297280 | 0.88 | ADRB2 (0.54) | ADRB2KCNH2TOP2ATOP2BGSK3B | |
| SCHEMBL7005951 | 0.87 | ADRB2 (0.57) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL7011806 | 0.87 | ADRB2 (0.59) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL7584091 | 0.85 | ADRB2 (0.57) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL9188190 | 0.85 | ADRB2 (0.61) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL7006273 | 0.84 | ADRB2 (0.56) | ADRB2KCNH2TOP2ATOP2BSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |