Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 20/20 | 0.62 |
| ▸ | HTR1D | P28221 | 18/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011873 | 1.00 | HTR1B (0.62) | HTR1BHTR1DHTR1A | |
| SCHEMBL7005968 | 1.00 | HTR1B (0.62) | HTR1BHTR1DHTR1A | |
| SCHEMBL7010803 | 1.00 | HTR1B (0.62) | HTR1BHTR1DHTR1A | |
| SCHEMBL7010593 | 0.82 | HTR1D (0.61) | HTR1BHTR1D | |
| SCHEMBL7006151 | 0.82 | HTR1D (0.63) | HTR1BHTR1DHTR1A | |
| SCHEMBL7006155 | 0.82 | HTR1D (0.63) | HTR1BHTR1DHTR1A | |
| SCHEMBL7006019 | 0.80 | HTR1B (0.61) | HTR1BHTR1DHTR1A | |
| SCHEMBL7011467 | 0.80 | HTR1B (0.61) | HTR1BHTR1DHTR1A | |
| SCHEMBL7012887 | 0.80 | HTR1B (0.61) | HTR1BHTR1DHTR1A | |
| SCHEMBL7012884 | 0.80 | HTR1B (0.61) | HTR1BHTR1DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | disclosed |
| US-6329390-B1 | BIHETEROCYCLIC INDOLES AS ANALGESICS AND NERVOUS SYSTEM DISORDERS | NPS ALLELIX CORP. (CA) | 2001-12-11 | — | — | US | disclosed |