Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 17/20 | 0.61 |
| ▸ | HTR1D | P28221 | 15/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006019 | 1.00 | HTR1B (0.61) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL7012884 | 1.00 | HTR1B (0.61) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL7011467 | 1.00 | HTR1B (0.61) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL7880763 | 0.89 | HTR1B (0.47) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL7006008 | 0.82 | HTR1D (0.62) | HTR1BHTR1D | |
| SCHEMBL7008669 | 0.81 | HTR1D (0.61) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL7008663 | 0.81 | HTR1D (0.61) | HTR1BHTR1DHTR1AHTR6 | |
| SCHEMBL7010803 | 0.80 | HTR1B (0.62) | HTR1BHTR1DHTR1A | |
| SCHEMBL7011873 | 0.80 | HTR1B (0.62) | HTR1BHTR1DHTR1A | |
| SCHEMBL7008355 | 0.80 | HTR1B (0.62) | HTR1BHTR1DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | disclosed |