SCHEMBL7008422

SCHEMBL7008422

C1=CC(c2nnc(-c3ccc(-c4nnc(-c5ccccc5)n4-c4ccccc4)cc3)o2)=CCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.43
NPC1 O15118 9/20 0.42
RAB9A P51151 9/20 0.42
SMN1; SMN2 Q16637 8/20 0.42
HPGD P15428 6/20 0.42
POLB P06746 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
TSHR P16473 5/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 2/20 0.42
NPSR1 Q6W5P4 3/20 0.42
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.38
GLA P06280 1/20 0.38
ALOX15 P16050 1/20 0.38
USP2 O75604 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24180801 0.96 HPGD (0.39) AVPR1ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL17425780 0.95 AVPR1A (0.43) AVPR1ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL16503278 0.85 NPC1 (0.57) NPC1RAB9ASMN1; SMN2HPGDPOLB
SCHEMBL17852254 0.84 AVPR1A (0.47) AVPR1ASMN1; SMN2HPGDTSHRALDH1A1
SCHEMBL19595241 0.83 AVPR1A (0.41) AVPR1ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL126271 0.83 NPC1 (0.61) AVPR1ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL13071795 0.81 NPC1 (0.55) NPC1RAB9ASMN1; SMN2HPGDPOLB
SCHEMBL20428172 0.80 AVPR1A (0.47) AVPR1ASMN1; SMN2HPGDTSHRALDH1A1
SCHEMBL21587049 0.79 AVPR1A (0.41) AVPR1ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL20124598 0.77 NPC1 (0.53) NPC1RAB9ASMN1; SMN2HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 EP disclosed
EP-3045465-B1 ORGANIC LIGHT EMITTING MATERIALS UNIVERSAL DISPLAY CORP (US) 2019-01-30 EP disclosed
EP-2574613-B1 Cyclometallated tetradentate Pt (II) complexes comprised of one or two imidazole rings with a twisted aryl group bonded to N-1 UNIVERSAL DISPLAY CORP (US) 2017-10-25 EP disclosed
EP-2539913-B1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2017-09-27 EP disclosed
WO-2012170571-A1 HETEROLEPTIC IRIDIUM CARBENE COMPLEXES AND LIGHT EMITTING DEVICE USING THEM UNIVERSAL DISPLAY CORPORATION (US) 2012-12-13 WO disclosed
WO-2012170461-A1 HETEROLEPTIC IRIDIUM CARBENE COMPLEXES AND LIGHT EMITTING DEVICE USING THEM UNIVERSAL DISPLAY CORPORATION (US) 2012-12-13 WO disclosed
WO-2012064499-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2012-05-18 WO disclosed
WO-2011109042-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-09 WO disclosed
WO-2010056669-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-05-20 WO disclosed
WO-2010033550-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-25 WO disclosed