SCHEMBL126271

SCHEMBL126271

c1ccc(-c2nnc(-c3ccc(-c4nnc(-c5ccccc5)n4-c4ccccc4)cc3)o2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.61
RAB9A P51151 9/20 0.61
SMN1; SMN2 Q16637 6/20 0.61
HPGD P15428 6/20 0.59
POLB P06746 1/20 0.59
NFKB1 P19838 1/20 0.59
NFKB2 Q00653 1/20 0.59
RELA Q04206 1/20 0.59
AVPR1A P37288 1/20 0.59
ALDH1A1 P00352 4/20 0.57
TSHR P16473 4/20 0.57
KDM4E B2RXH2 3/20 0.57
HSD17B10 Q99714 3/20 0.57
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
NPSR1 Q6W5P4 2/20 0.53
GLA P06280 2/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53
ATAD2 Q6PL18 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4402535 0.85 AVPR1A (0.78) SMN1; SMN2HPGDAVPR1AALDH1A1TSHR
SCHEMBL8339889 0.85 AVPR1A (0.78) SMN1; SMN2HPGDAVPR1AALDH1A1TSHR
SCHEMBL18327898 0.84 AVPR1A (0.70) SMN1; SMN2HPGDAVPR1AALDH1A1TSHR
SCHEMBL39449 0.84 AVPR1A (0.70) SMN1; SMN2HPGDAVPR1AALDH1A1TSHR
SCHEMBL18884735 0.84 AVPR1A (0.43) NPC1RAB9ASMN1; SMN2HPGDPOLB
SCHEMBL7008422 0.83 AVPR1A (0.43) NPC1RAB9ASMN1; SMN2HPGDPOLB
SCHEMBL7553280 0.83 SMN1; SMN2 (0.49) NPC1RAB9ASMN1; SMN2HPGDPOLB
SCHEMBL17425780 0.83 AVPR1A (0.43) NPC1RAB9ASMN1; SMN2HPGDPOLB
SCHEMBL13815005 0.81 AVPR1A (0.62) SMN1; SMN2HPGDAVPR1AALDH1A1TSHR
SCHEMBL21587049 0.81 AVPR1A (0.41) NPC1RAB9ASMN1; SMN2HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029108-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-02 US disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
EP-4329431-A2 NOVEL HETEROLEPTIC IRIDIUM COMPLEXES Universal Display Corporation (US) 2024-02-28 EP disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
WO-2010002848-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2010-01-07 WO disclosed
WO-2010002850-A1 HOLE TRANSPORT MATERIALS CONTAINING TRIPHENYLENE UNIVERSAL DISPLAY CORPORATION (US) 2010-01-07 WO disclosed
US-20090200927-A1 ORGANIC LIGHT EMITTING DEVICE ARCHITECTURE UNIVERSAL DISPLAY CORPORATION (US) 2009-08-13 US disclosed
US-20090200927-A1 ORGANIC LIGHT EMITTING DEVICE ARCHITECTURE UNIVERSAL DISPLAY CORPORATION (US) 2009-08-13 US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 NPC1 4125/4885RAB9A 3612/4885SMN1; SMN2 3183/4885
US-12029108-B2 Organic electroluminescent materials and devices LBR, DBF4, DNMT3A NPC1 3848/4885RAB9A 1710/4885SMN1; SMN2 4267/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 NPC1 3991/4885RAB9A 1630/4885SMN1; SMN2 3913/4885
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR NPC1 2166/4885RAB9A 1869/4885SMN1; SMN2 3782/4885
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 NPC1 2962/4885RAB9A 3802/4885SMN1; SMN2 4772/4885
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES PAICS, CYBA, OXA1L NPC1 3252/4885RAB9A 3336/4885SMN1; SMN2 4743/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM NPC1 2492/4885RAB9A 2738/4885SMN1; SMN2 3557/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR NPC1 2166/4885RAB9A 1869/4885SMN1; SMN2 3782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.