Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005800 | 0.89 | NPSR1 (0.53) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL6182752 | 0.86 | NPSR1 (0.55) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL7007726 | 0.82 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL8703669 | 0.78 | KMT2A (0.48) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL8708406 | 0.76 | NPSR1 (0.49) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL8707006 | 0.76 | NPSR1 (0.49) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL29505034 | 0.74 | KDM4E (0.54) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL22719839 | 0.74 | KDM4E (0.54) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL8030601 | 0.74 | ALDH1A1 (0.49) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 | |
| SCHEMBL7011308 | 0.74 | S1PR1 (0.47) | CYP1A2CYP2C9CYP2C19NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | claimed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-6066597-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| US-6008161-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero) aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5849758-A | Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5824624-A | HERBICIDES WITH CARRIERS OR SURFACTANTS | AMERICAN CYANAMID COMPANY (US) | 1998-10-20 | — | — | US | disclosed |