Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 5/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014855 | 0.88 | TOP1 (0.42) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL7011369 | 0.86 | PRKD3 (0.43) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL6806741 | 0.84 | PIM1 (0.43) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL7013934 | 0.75 | PRKD3 (0.39) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL7007951 | 0.74 | MEN1 (0.50) | ALDH1A1KMT2A | |
| SCHEMBL6797144 | 0.73 | PRKD3 (0.45) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL6800903 | 0.72 | F10 (0.40) | TOP1PIM1PIM3TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7006179 | 0.72 | PRKD3 (0.44) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL7013172 | 0.71 | TOP1 (0.47) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL6798617 | 0.71 | PRKD3 (0.44) | TOP1PRKD3PIM1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028950-B1 | 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2003-05-02 | — | — | EP | claimed |