Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 8/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013934 | 0.85 | PRKD3 (0.39) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL7015316 | 0.83 | GSK3B (0.34) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL6795074 | 0.82 | TOP1 (0.54) | TOP1KCNH2PRKD3PIM1GSK3A | |
| SCHEMBL4517467 | 0.81 | TOP1 (0.65) | TOP1KCNH2PRKD3PIM1GSK3A | |
| Hydrochloric Acid SCHEMBL4524334 | 0.80 | TOP1 (0.64) | TOP1KCNH2PRKD3PIM1GSK3A | |
| SCHEMBL7010855 | 0.77 | KDM4E (0.41) | TOP1 | |
| SCHEMBL7535211 | 0.77 | KDM4E (0.41) | TOP1 | |
| SCHEMBL7011369 | 0.76 | PRKD3 (0.43) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL7014855 | 0.72 | TOP1 (0.42) | TOP1PRKD3PIM1GSK3AGSK3B | |
| SCHEMBL7008713 | 0.71 | TOP1 (0.41) | TOP1PRKD3PIM1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028950-B1 | 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2003-05-02 | — | — | EP | claimed |