Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 14/20 | 0.41 |
| ▸ | CA1 | P00915 | 12/20 | 0.41 |
| ▸ | CA4 | P22748 | 12/20 | 0.41 |
| ▸ | CA9 | Q16790 | 12/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008837 | 1.00 | ALDH1A1 (0.43) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL5172094 | 0.86 | KMT2A (0.47) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL5428534 | 0.86 | KMT2A (0.47) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL5430345 | 0.84 | ALDH1A1 (0.46) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL5169077 | 0.84 | ALDH1A1 (0.46) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL5430362 | 0.83 | ALDH1A1 (0.46) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL5430358 | 0.83 | ALDH1A1 (0.46) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL7654637 | 0.82 | TLK2 (0.47) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL12856336 | 0.82 | TLK2 (0.47) | ALDH1A1PKMHPGDMAPK1L3MBTL1 | |
| SCHEMBL7013827 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPK1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180105-B1 | SUBSTITUTED AZA-OXINDOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-05-14 | — | — | EP | claimed |