Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006088 | 0.93 | TOP2A (0.56) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL7006628 | 0.85 | TOP2A (0.56) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| Bromide SCHEMBL7012863 | 0.84 | TOP2A (0.56) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL7006195 | 0.81 | TOP2A (0.55) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL7006246 | 0.81 | TOP2A (0.58) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL7866482 | 0.81 | TOP2A (0.67) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL7010658 | 0.80 | TOP2A (0.57) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL4996744 | 0.79 | TOP2A (0.52) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL4998670 | 0.78 | TOP2A (0.52) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL5001621 | 0.78 | TOP2A (0.49) | TOP2ATOP2BKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |