SCHEMBL7008879

SCHEMBL7008879

CNc1ccc(N(C)c2ccc(N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
CYP3A4 P08684 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
MAPK1 P28482 2/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.40
TSHR P16473 2/20 0.40
PSMD14 O00487 1/20 0.40
RECQL P46063 1/20 0.40
GFER P55789 1/20 0.40
EGFR P00533 1/20 0.40
PDGFRB P09619 1/20 0.40
KDR P35968 1/20 0.40
NR3C2 P08235 1/20 0.39
HTR6 P50406 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7011380 0.94 CYP3A4 (0.45) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL11510806 0.89 TSHR (0.46) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL9694680 0.87 ALDH1A1 (0.70) ALDH1A1CYP3A4TDP1MAPK1TP53
Hydrochloric Acid SCHEMBL9694676 0.85 ALDH1A1 (0.67) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL525926 0.83
SCHEMBL7877908 0.83 ALDH1A1 (0.68) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL64766 0.83 ALDH1A1 (0.68) ALDH1A1CYP3A4TDP1MAPK1TP53
SCHEMBL21474106 0.83 ALDH1A1 (0.68) ALDH1A1CYP3A4TDP1MAPK1TP53
Ammonia Solution, Strong SCHEMBL11052046 0.81 TSHR (0.48) ALDH1A1CYP3A4TDP1TP53ALOX15
Hydrochloric Acid SCHEMBL6010014 0.81 TSHR (0.48) ALDH1A1CYP3A4TDP1TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219112-A1 NOVEL DIAMINE COMPOUND, POLYMER OBTAINED USING DIAMINE, LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-11-16 WO disclosed
EP-0995786-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2003-01-08 EP disclosed
US-6208452-B1 HAS AN ION CONDUCTIVE LAYER OBTAINED BY CURING A COMPOSITION COMPRISING A BIPYRIDINIUM COMPOUND, A SPECIFIC AMINE COMPOUND AND A PRECURSOR COMPONENT OF A POLYMERIC SOLID ELECTROLYTE DISPOSED BETWEEN TWO ELECTRICALLY CONDUCTIVE SUBSTRATES NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-27 US disclosed
US-6203154-B1 MULTILAYER NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-20 US disclosed
EP-1041425-A1 ELECTROCHROMIC ELEMENT Nippon Mitsubishi Oil Corporation (JP) 2000-10-04 EP disclosed
EP-0995786-A1 Electrochromic device Nippon Mitsubishi Oil Corporation (JP) 2000-04-26 EP disclosed