Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580381 | 0.87 | KMT2A (0.54) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL10583115 | 0.87 | KMT2A (0.54) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL10580642 | 0.87 | KMT2A (0.54) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL10584743 | 0.84 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1FFAR1 | |
| SCHEMBL7018609 | 0.84 | KMT2A (0.55) | KMT2AMEN1HTTALDH1A1APEX1 | |
| SCHEMBL10584735 | 0.84 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1FFAR1 | |
| SCHEMBL1201074 | 0.83 | KMT2A (0.71) | KMT2AMEN1HTTALDH1A1APEX1 | |
| SCHEMBL13870211 | 0.82 | KMT2A (1.00) | KMT2AMEN1ALDH1A1APEX1POLB | |
| SCHEMBL831127 | 0.81 | KMT2A (0.51) | KMT2AMEN1HTTPOLBLMNA | |
| SCHEMBL7012775 | 0.80 | KMT2A (0.54) | KMT2AMEN1HTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | KMT2A 636/4885MEN1 1401/4885HTT 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.