Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580381 | 1.00 | KMT2A (0.54) | KMT2AMEN1HTTLTB4RALDH1A1 | |
| SCHEMBL10580642 | 1.00 | KMT2A (0.54) | KMT2AMEN1HTTLTB4RALDH1A1 | |
| SCHEMBL7008951 | 0.87 | KMT2A (0.70) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL10583160 | 0.86 | LTB4R (0.51) | KMT2AMEN1HTTLTB4RALDH1A1 | |
| SCHEMBL10583969 | 0.86 | LTB4R (0.51) | KMT2AMEN1HTTLTB4RALDH1A1 | |
| SCHEMBL1007571 | 0.85 | MAPT (0.58) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL9813452 | 0.79 | TBXA2R (0.53) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL10584743 | 0.79 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL10584735 | 0.79 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL10800449 | 0.78 | KMT2A (0.57) | KMT2AMEN1HTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |