Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 8/20 | 0.41 |
| ▸ | RORC | P51449 | 8/20 | 0.41 |
| ▸ | RORB | Q92753 | 8/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 6/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5231967 | 0.99 | RORA (0.41) | RORARORCRORBDPP4PGR | |
| Hydrochloric Acid SCHEMBL5237070 | 0.95 | RORA (0.43) | RORARORCRORBDPP4PGR | |
| SCHEMBL5239031 | 0.90 | RORA (0.44) | RORARORCRORBPGRPTGDR2 | |
| SCHEMBL5236096 | 0.90 | RORA (0.41) | RORARORCRORBDPP4PGR | |
| Hydrochloric Acid SCHEMBL5234632 | 0.86 | DPP4 (0.41) | DPP4PARP1PARP2 | |
| Hydrochloric Acid SCHEMBL5238860 | 0.86 | DPP4 (0.42) | DPP4PGR | |
| SCHEMBL5233756 | 0.85 | RORA (0.46) | RORARORCRORBDPP4PGR | |
| SCHEMBL5235895 | 0.85 | RORA (0.44) | RORARORCRORBDPP4PGR | |
| Hydrochloric Acid SCHEMBL5237526 | 0.85 | DPP4 (0.41) | RORARORCRORBDPP4PGR | |
| SCHEMBL5235827 | 0.84 | RORA (0.40) | RORARORCRORBPGRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062764-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-15 | — | — | WO | disclosed |