Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.34 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013423 | 0.84 | STAT3 (0.43) | STAT3ADRB2HPGDALDH1A1LMNA | |
| SCHEMBL8184167 | 0.81 | STAT3 (0.44) | STAT3ADRB2HPGDALDH1A1LMNA | |
| SCHEMBL7013788 | 0.78 | STAT3 (0.41) | STAT3ADRB2HPGDALDH1A1LMNA | |
| SCHEMBL7009121 | 0.78 | PIM1 (0.37) | STAT3ADRB2HPGDALDH1A1LMNA | |
| SCHEMBL7011781 | 0.76 | STAT3 (0.39) | STAT3ALDH1A1KDM4EHTTNPC1 | |
| SCHEMBL7005450 | 0.68 | STAT3 (0.48) | STAT3ADRB2HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL19728752 | 0.66 | ADRB2 (0.39) | STAT3ADRB2HPGDALDH1A1LMNA | |
| SCHEMBL7009112 | 0.66 | STAT3 (0.46) | STAT3ADRB2HPGDALDH1A1LMNA | |
| SCHEMBL19728358 | 0.66 | STAT3 (0.41) | STAT3ADRB2HPGDALDH1A1LMNA | |
| SCHEMBL7004211 | 0.65 | STAT3 (0.53) | STAT3ADRB2HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |