Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.48 |
| ▸ | CTSL | P07711 | 13/20 | 0.45 |
| ▸ | CTSS | P25774 | 13/20 | 0.45 |
| ▸ | CTSB | P07858 | 5/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006534 | 0.85 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7148228 | 0.82 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7099951 | 0.80 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7427143 | 0.79 | CTSK (0.53) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6409859 | 0.77 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6409369 | 0.77 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4765007 | 0.75 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4824107 | 0.75 | CTSK (0.51) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7565605 | 0.74 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7095942 | 0.74 | CTSK (0.58) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278502-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-1278502-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001089451-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |