Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011913 | 0.87 | PIM1 (0.51) | PIM1TOP1TOP2ACYP3A4CYP2C9 | |
| Monoethanolamine SCHEMBL7009594 | 0.85 | PIM1 (0.50) | PIM1TOP1TOP2ACYP3A4CYP2C9 | |
| SCHEMBL7006968 | 0.85 | CYP3A4 (0.50) | PIM1TOP1TOP2AADRB2CYP3A4 | |
| SCHEMBL7012642 | 0.82 | PIM1 (0.50) | PIM1TOP1TOP2AADRB2CYP3A4 | |
| SCHEMBL7009088 | 0.81 | PIM1 (0.52) | PIM1TOP1TOP2ACYP3A4CYP2C9 | |
| SCHEMBL7099804 | 0.80 | PIM1 (0.47) | PIM1TOP1TOP2AADRB2CYP3A4 | |
| SCHEMBL20912644 | 0.80 | ADRB2 (0.42) | PIM1TOP1TOP2AADRB2STAT3 | |
| SCHEMBL19728783 | 0.79 | PIM1 (0.49) | PIM1TOP1TOP2ACYP3A4CYP2C9 | |
| SCHEMBL7009334 | 0.79 | PIM1 (0.48) | PIM1TOP1TOP2ACYP3A4CYP2C9 | |
| SCHEMBL7011538 | 0.78 | PIM1 (0.51) | PIM1TOP1TOP2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6136823-A | BACTERICIDES OR VIRICIDES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0945435-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |