Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643390 | 0.94 | DPP4 (0.64) | DPP4ALDH1A1TSHRHTTUSP2 | |
| SCHEMBL5642756 | 0.91 | DPP4 (0.66) | DPP4ALDH1A1TSHRHTTUSP2 | |
| SCHEMBL5641325 | 0.91 | DPP4 (0.62) | DPP4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL7093975 | 0.89 | DPP4 (0.55) | DPP4ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL14524051 | 0.86 | DPP4 (0.60) | DPP4ALDH1A1TSHRHTTUSP2 | |
| SCHEMBL555889 | 0.86 | DPP4 (0.71) | DPP4ALDH1A1TSHRHTTUSP2 | |
| SCHEMBL5641163 | 0.85 | DPP4 (0.67) | DPP4ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL7007302 | 0.85 | DPP4 (0.55) | DPP4ALDH1A1L3MBTL1 | |
| SCHEMBL5640234 | 0.85 | DPP4 (0.55) | DPP4ALDH1A1L3MBTL1 | |
| SCHEMBL7009959 | 0.84 | DPP4 (0.53) | DPP4ALDH1A1TSHRHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301187-A2 | HETEROCYCLIC COMPOUNDS, WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | claimed |
| WO-2002002560-A2 | PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) | NOVO NORDISK A/S (DK) | 2002-01-10 | — | — | WO | claimed |