Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17926602 | 0.79 | GRM1 (0.36) | SMPD3GRM5GRM1ENPP3ENPP1 | |
| SCHEMBL6611594 | 0.77 | CCR1 (0.38) | LMNAMAPTKDM4EHTT | |
| SCHEMBL31096943 | 0.76 | LMNA (0.33) | LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL23331997 | 0.68 | ADORA1 (0.42) | SMPD3GRM5GRM1KDM4EALDH1A1 | |
| SCHEMBL9062564 | 0.67 | LMNA (0.31) | LMNAMAPT | |
| SCHEMBL10328322 | 0.67 | GRM1 (0.39) | GRM5GRM1LMNAKDM4EALDH1A1 | |
| SCHEMBL25098010 | 0.67 | SMPD3 (0.34) | SMPD3GRM5GRM1KDM4EALDH1A1 | |
| SCHEMBL23697044 | 0.67 | SMPD3 (0.34) | SMPD3GRM5GRM1KDM4EALDH1A1 | |
| SCHEMBL24896144 | 0.64 | GRM1 (0.33) | SMPD3GRM5GRM1ENPP3ENPP1 | |
| SCHEMBL18510385 | 0.64 | ADORA2A (0.46) | GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662078-B1 | REAGENTS FOR PEPTIDE COUPLINGS | RES CORP TECHNOLOGIES INC (US) | 2003-05-02 | — | — | EP | disclosed |
| US-RE38073-E1 | Biosynthesis; using dehydration agent | RESEARCH CORPORATIONS TECHNOLOGIES, INC. | 2003-04-08 | — | — | US | disclosed |
| US-RE37686-E1 | Azahydroxybenzotriazoles and derivatives thereof for peptide coupling reactions | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-5698675-A | AMIDATION; ESTERIFICATION | RESEARCH CORPORATION TECH., INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5644029-A | TRIAZOLO-PYRIDINE HETEROCYCLIC COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5580981-A | YELLOW INDICATORS FADING TO COLORLESS UPON COMPLETION OF THE ACYLATION STEP IN AMIDE FORMATION; REACTION ACCELERATORS; LOWERS RACEMIZATION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| WO-1994007910-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |