Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 3/20 | 0.70 |
| ▸ | RORC | P51449 | 16/20 | 0.48 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.44 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.44 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.44 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007270 | 0.94 | BDKRB2 (0.72) | BDKRB2RORC | |
| SCHEMBL7005536 | 0.94 | BDKRB2 (0.72) | BDKRB2RORC | |
| SCHEMBL7014632 | 0.93 | BDKRB2 (0.61) | BDKRB2RORCGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL7014628 | 0.93 | BDKRB2 (0.61) | BDKRB2RORCGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL7718833 | 0.93 | BDKRB2 (0.70) | BDKRB2RORC | |
| SCHEMBL7719872 | 0.93 | BDKRB2 (0.70) | BDKRB2RORC | |
| SCHEMBL7008616 | 0.93 | BDKRB2 (0.70) | BDKRB2RORC | |
| Hydrochloric Acid SCHEMBL7722639 | 0.92 | BDKRB2 (0.70) | BDKRB2RORC | |
| SCHEMBL7006073 | 0.92 | BDKRB2 (0.60) | BDKRB2RORCGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL7006076 | 0.92 | BDKRB2 (0.60) | BDKRB2RORCGUCY1B2GUCY1A2GUCY1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991650-B1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER IND & SANTE (FR) | 2003-09-10 | — | — | EP | disclosed |
| US-6384222-B1 | BRADYKININ HORMONE ANTAGONIST; ANALGESIC, ANTIINFLAMMATORY; ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS; ETHERIFICATION, AMIDATION | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-05-07 | — | — | US | disclosed |
| EP-0991650-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000387-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-01-07 | — | — | WO | disclosed |