SCHEMBL7010244

SCHEMBL7010244

CC(CCCCCSc1ncc(Cc2ccn(C)c(=O)c2)c(=O)[nH]1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7009365 0.87 PLA2G7 (1.00) PLA2G7
SCHEMBL7010449 0.87 PLA2G7 (1.00) PLA2G7
SCHEMBL7009604 0.87 PLA2G7 (1.00) PLA2G7
SCHEMBL7005486 0.87 PLA2G7 (1.00) PLA2G7
SCHEMBL7009237 0.83 PLA2G7 (0.79) PLA2G7
SCHEMBL7006822 0.81 PLA2G7 (0.75) PLA2G7
SCHEMBL7007398 0.77 PLA2G7 (1.00) PLA2G7
SCHEMBL7008900 0.76 PLA2G7 (1.00) PLA2G7
SCHEMBL7008535 0.75 PLA2G7 (0.80) PLA2G7
SCHEMBL7008941 0.75 PLA2G7 (0.80) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028955-B1 PYRIMIDINONE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SMITHKLINE BEECHAM PLC (GB) 2003-07-16 EP claimed