Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2677181 | 0.81 | — | — | |
| SCHEMBL17595079 | 0.73 | — | — | |
| SCHEMBL14777112 | 0.73 | — | — | |
| SCHEMBL11651861 | 0.73 | — | — | |
| SCHEMBL775953 | 0.73 | — | — | |
| SCHEMBL3618771 | 0.71 | — | — | |
| SCHEMBL7631120 | 0.69 | MAPT (0.35) | — | |
| SCHEMBL28459258 | 0.68 | — | — | |
| SCHEMBL15659260 | 0.68 | — | — | |
| SCHEMBL17785527 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161271-A1 | Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl | Università Degli Studi Di Milano - Bicocca (IT) | 2010-03-10 | — | — | EP | disclosed |
| CN-1183126-C | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | ���±ȶ��ش�ѧ | 2005-01-05 | — | — | CN | disclosed |
| EP-1358161-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Amgen Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002055501-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMGEN INC (US) | 2002-07-18 | — | — | WO | disclosed |
| CN-1157613-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | PROCTER & GAMBLE (US) | 1997-08-20 | — | — | CN | disclosed |