Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | USP25 | Q9UHP3 | 4/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535211 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Trifluoroacetic Acid SCHEMBL7535209 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6805232 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6802003 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7013934 | 0.83 | PRKD3 (0.39) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7015316 | 0.81 | GSK3B (0.34) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7013172 | 0.77 | TOP1 (0.47) | TOP1 | |
| SCHEMBL606463 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL608171 | 0.71 | — | — | |
| SCHEMBL6215994 | 0.71 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028950-B1 | 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2003-05-02 | — | — | EP | claimed |