Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202112 | 0.79 | TSHR (0.57) | TSHRPOLBCHRNB4CHRNA3DPP4 | |
| SCHEMBL1778423 | 0.79 | TSHR (0.57) | TSHRPOLBCHRNB4CHRNA3DPP4 | |
| SCHEMBL2681321 | 0.79 | TSHR (0.57) | TSHRPOLBCHRNB4CHRNA3DPP4 | |
| SCHEMBL1115598 | 0.79 | HSD17B10 (0.52) | TSHRL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL559852 | 0.79 | HSD17B10 (0.52) | TSHRL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1010839 | 0.79 | HSD17B10 (0.52) | TSHRL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1550543 | 0.79 | HSD17B10 (0.52) | TSHRL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7527261 | 0.78 | TSHR (0.45) | TSHRPOLBCHRNB4CHRNA3RAB9A | |
| Hydrochloric Acid SCHEMBL2057759 | 0.78 | TSHR (0.55) | TSHRPOLBCHRNB4CHRNA3DPP4 | |
| SCHEMBL3863785 | 0.78 | TSHR (0.45) | TSHRPOLBCHRNB4CHRNA3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2410844-B1 | INHIBITORS OF HEPATITIS C VIRUS REPLICATION | MERCK SHARP & DOHME (US) | 2016-03-23 | — | — | EP | disclosed |
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |