Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 16/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | JAK3 | P52333 | 3/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647566 | 0.92 | NPY1R (0.46) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7017021 | 0.91 | NPY1R (0.46) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7012025 | 0.90 | NPY1R (0.45) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7018703 | 0.90 | NPY1R (0.45) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7019510 | 0.90 | NPY1R (0.45) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7102412 | 0.89 | NPY1R (0.53) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL8057456 | 0.87 | NPY1R (0.49) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7016590 | 0.87 | NPY1R (0.57) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7015274 | 0.87 | NPY1R (0.46) | NPY1RJAK2JAK3JAK1TTK | |
| SCHEMBL7015755 | 0.87 | NPY1R (0.54) | NPY1RJAK2JAK3JAK1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |