Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.84 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | UBE2N | P61088 | 2/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.66 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.65 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7019827 | 0.99 | LMNA (0.82) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL20561174 | 0.92 | LMNA (1.00) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7018390 | 0.91 | LMNA (0.69) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7011204 | 0.91 | LMNA (0.68) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7018070 | 0.91 | LMNA (0.68) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7018193 | 0.91 | SMN1; SMN2 (0.72) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7011398 | 0.90 | LMNA (0.67) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7017901 | 0.90 | LMNA (0.67) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7015993 | 0.89 | LMNA (0.66) | LMNAMAPK1ADORA2BSMN1; SMN2HTT | |
| SCHEMBL7015123 | 0.89 | LMNA (0.66) | LMNAMAPK1ADORA2BSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |