Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328332 | 0.99 | HTR3A (0.45) | HTR3ASIGMAR1RORCCHRNA7USP30 | |
| SCHEMBL699893 | 0.99 | HTR3A (0.45) | HTR3ASIGMAR1RORCCHRNA7USP30 | |
| SCHEMBL699894 | 0.99 | HTR3A (0.45) | HTR3ASIGMAR1RORCCHRNA7USP30 | |
| Lithium Ion SCHEMBL702639 | 0.91 | HTR3A (0.43) | HTR3ASIGMAR1CHRNA7USP30 | |
| Lithium Ion SCHEMBL701115 | 0.91 | HTR3A (0.43) | HTR3ASIGMAR1CHRNA7USP30 | |
| SCHEMBL702083 | 0.91 | HTR3A (0.45) | HTR3ARORCCHRNA7USP30 | |
| SCHEMBL701557 | 0.91 | HTR3A (0.42) | HTR3ASIGMAR1 | |
| SCHEMBL700053 | 0.91 | HTR3A (0.42) | HTR3ASIGMAR1 | |
| SCHEMBL700054 | 0.91 | HTR3A (0.42) | HTR3ASIGMAR1 | |
| SCHEMBL701109 | 0.90 | HTR3A (0.46) | HTR3ARORCCHRNA7USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124600-B2 | 5-HT3 receptor modulators, methods of making, and use thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2310019-A2 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | Albany Molecular Research, Inc. (US) | 2011-04-20 | — | — | EP | disclosed |