Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329718 | 0.99 | CHRNA7 (0.48) | CHRNA7HTR3APARP1GAASMN1; SMN2 | |
| SCHEMBL4329712 | 0.99 | CHRNA7 (0.48) | CHRNA7HTR3APARP1GAASMN1; SMN2 | |
| SCHEMBL9234400 | 0.89 | CHRNA7 (0.47) | CHRNA7HTR3APARP1 | |
| Lithium Ion SCHEMBL701123 | 0.89 | CHRNA7 (0.47) | CHRNA7HTR3APARP1GAASMN1; SMN2 | |
| SCHEMBL9234393 | 0.89 | CHRNA7 (0.47) | CHRNA7HTR3APARP1 | |
| SCHEMBL703665 | 0.88 | CHRNA7 (0.46) | CHRNA7HTR3APARP1 | |
| SCHEMBL703666 | 0.88 | CHRNA7 (0.46) | CHRNA7HTR3APARP1 | |
| SCHEMBL1079078 | 0.84 | HTR3A (0.39) | CHRNA7HTR3APARP1 | |
| SCHEMBL700032 | 0.83 | CHRNA7 (0.40) | CHRNA7HTR3APARP1GAASMN1; SMN2 | |
| SCHEMBL700033 | 0.83 | CHRNA7 (0.40) | CHRNA7HTR3APARP1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124600-B2 | 5-HT3 receptor modulators, methods of making, and use thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2310019-A2 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | Albany Molecular Research, Inc. (US) | 2011-04-20 | — | — | EP | disclosed |