Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639551 | 0.93 | DPP4 (0.68) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL5640069 | 0.90 | DPP4 (0.78) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL5641434 | 0.89 | DPP4 (0.73) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL5643484 | 0.89 | DPP4 (0.73) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL464943 | 0.84 | DPP4 (0.77) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL555986 | 0.83 | DPP4 (0.92) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL5640138 | 0.81 | DPP4 (0.71) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL5640222 | 0.81 | DPP4 (0.71) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL5640131 | 0.81 | DPP4 (0.71) | DPP4ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL5323627 | 0.81 | DPP4 (1.00) | DPP4ALDH1A1TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301187-A2 | HETEROCYCLIC COMPOUNDS, WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | claimed |
| WO-2002002560-A2 | PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) | NOVO NORDISK A/S (DK) | 2002-01-10 | — | — | WO | claimed |