Sugi Predict

Sugi Predict / Compounds / SCHEMBL5323627

SCHEMBL5323627

SCHEMBL5323627

Cn1c(=O)c2c(nc(N3CCNCC3)n2Cc2ccccc2)n(C)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 9/20 1.00
▸ L3MBTL1 Q9Y468 1/20 0.77
▸ ALDH1A1 P00352 7/20 0.76
▸ NPSR1 Q6W5P4 4/20 0.76
▸ TSHR P16473 3/20 0.76
▸ MAPK1 P28482 2/20 0.76
▸ RECQL P46063 1/20 0.76
▸ MAPT P10636 3/20 0.68
▸ TDP1 Q9NUW8 1/20 0.68
▸ LMNA P02545 3/20 0.66
▸ USP2 O75604 2/20 0.66
▸ SMN1; SMN2 Q16637 1/20 0.66
▸ MEN1 O00255 2/20 0.65
▸ KMT2A Q03164 2/20 0.65
▸ ALOX15 P16050 2/20 0.65
▸ HSD17B10 Q99714 2/20 0.65
▸ KDM4E B2RXH2 1/20 0.65
▸ HPGD P15428 1/20 0.65
▸ HIF1A Q16665 1/20 0.63
▸ FAP Q12884 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL555986 0.96 DPP4 (0.92) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL5642868 0.94 DPP4 (0.88) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL554778 0.93 DPP4 (0.87) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL5642195 0.90 DPP4 (0.81) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL5643509 0.90 DPP4 (0.82) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL8339602 0.90 ALDH1A1 (0.81) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL5642832 0.89 DPP4 (0.80) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL555168 0.89 DPP4 (0.80) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL5641790 0.88 DPP4 (0.79) DPP4L3MBTL1ALDH1A1NPSR1TSHR
SCHEMBL5640069 0.88 DPP4 (0.78) DPP4L3MBTL1ALDH1A1NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3961741-B1 DISPLAY PANEL SAMSUNG DISPLAY CO LTD (KR) 2024-10-16 — — EP claimed
CN-118325898-A Application of compound in preparation of medicine for preventing and treating poplar canker 浙江农林大学 2024-07-12 — — CN claimed
US-7235538-B2 Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV NOVO NORDISK A/S (DK) 2007-06-26 — — US claimed
EP-1561752-A1 Heterocyclic compounds that are inhibitors of the enzyme DPP-IV NOVO NORDISK A/S (DK) 2005-08-10 — — EP claimed
EP-1301187-B1 PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) NOVO NORDISK AS (DK) 2005-07-06 — — EP claimed
EP-1301187-A2 HETEROCYCLIC COMPOUNDS, WHICH ARE INHIBITORS OF THE ENZYME DPP-IV NOVO NORDISK A/S (DK) 2003-04-16 — — EP claimed
US-20020161001-A1 Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV NOVO NORDISK A/S (DK) 2002-10-31 — — US claimed
WO-2002002560-A2 PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) NOVO NORDISK A/S (DK) 2002-01-10 — — WO claimed
US-20250338743-A1 DISPLAY PANEL SAMSUNG DISPLAY CO LTD (KR) 2025-10-30 — — US disclosed
US-20250240826-A1 METHOD AND APPARATUS FOR RANDOM ACCESS IN A WIRELESS COMMUNICATION SYSTEM ASUS TECHNOLOGY LICENSING INC. (TW) 2025-07-24 — — US disclosed
US-12369475-B2 Display panel with spacers every four or more pixels SAMSUNG DISPLAY CO., LTD. (KR) 2025-07-22 — — US disclosed
CN-118908901-A Method for continuously synthesizing aminophylline intermediate 2 through nitrosation 台州普渡机械设备有限公司 2024-11-08 — — CN disclosed
EP-3961741-B1 DISPLAY PANEL SAMSUNG DISPLAY CO LTD (KR) 2024-10-16 — — EP disclosed
CN-118325898-A Application of compound in preparation of medicine for preventing and treating poplar canker 浙江农林大学 2024-07-12 — — CN disclosed
WO-2005037779-A2 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES IMTM GMBH (DE) 2005-04-28 — — WO disclosed
WO-2005025554-A2 DIPEPTIDYL PEPTIDASE IV INHIBITOR JAPAN TOBACCO INC. (JP) 2005-03-24 — — WO disclosed
US-20040034014-A1 Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV KANSTRUP ANDERS BENDTZ (DK) 2004-02-19 — — US disclosed
EP-1301187-A2 HETEROCYCLIC COMPOUNDS, WHICH ARE INHIBITORS OF THE ENZYME DPP-IV NOVO NORDISK A/S (DK) 2003-04-16 — — EP disclosed
US-20020161001-A1 Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV NOVO NORDISK A/S (DK) 2002-10-31 — — US disclosed
WO-2002002560-A2 PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) NOVO NORDISK A/S (DK) 2002-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040034014-A1 Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV DPP4, DPP7, DPP3 DPP4 1/4885L3MBTL1 1646/4885ALDH1A1 360/4885
US-20020161001-A1 Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV DPP4, DPP7, DPP3 DPP4 1/4885L3MBTL1 1646/4885ALDH1A1 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.