Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23836089 | 0.76 | IDO1 (0.46) | KMT2AMAPTALDH1A1GAATDP1 | |
| SCHEMBL7310972 | 0.76 | IDO1 (0.46) | KMT2AMAPTALDH1A1GAATDP1 | |
| SCHEMBL18025745 | 0.75 | PDE4A (0.55) | KMT2AMAPTALDH1A1TTRGAA | |
| SCHEMBL24740261 | 0.73 | IDO1 (0.48) | KMT2AMAPTALDH1A1GAATDP1 | |
| SCHEMBL24740169 | 0.73 | IDO1 (0.48) | KMT2AMAPTALDH1A1GAATDP1 | |
| SCHEMBL12520453 | 0.73 | IDO1 (0.44) | KMT2AMAPTALDH1A1GAATDP1 | |
| SCHEMBL18853924 | 0.72 | TP53 (0.51) | MAPTALDH1A1TP53LMNATHRB | |
| SCHEMBL14555907 | 0.72 | MAOB (0.57) | MAPTALDH1A1TP53LMNATHRB | |
| SCHEMBL18025766 | 0.71 | GSK3B (0.68) | MAPTALDH1A1GAAKDM4EPOLB | |
| SCHEMBL9774494 | 0.69 | SLC6A2 (0.43) | KMT2AMAPTTDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815859-B1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-5977130-A | CARDIOVASCULAR DISORDERS | TAIHO PHARMEUTICAL CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0815859-A1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |