Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 15/20 | 0.56 |
| ▸ | RORC | P51449 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014202 | 0.85 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL7014199 | 0.85 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL8018900 | 0.81 | BDKRB2 (0.47) | BDKRB2 | |
| SCHEMBL7016917 | 0.80 | BDKRB2 (0.49) | BDKRB2 | |
| SCHEMBL8724025 | 0.76 | BDKRB2 (0.58) | BDKRB2RORC | |
| SCHEMBL13145018 | 0.76 | BDKRB2 (0.72) | BDKRB2RORC | |
| SCHEMBL7007131 | 0.75 | BDKRB2 (0.61) | BDKRB2RORC | |
| SCHEMBL13145764 | 0.74 | BDKRB2 (0.66) | BDKRB2RORCCYP3A4 | |
| SCHEMBL13145034 | 0.73 | BDKRB2 (0.61) | BDKRB2RORC | |
| SCHEMBL13145507 | 0.73 | BDKRB2 (0.66) | BDKRB2RORCCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861243-B1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-6344462-B1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| US-6100284-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-6008229-A | TREATING ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE, SHOCK, PAIN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0861243-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997011069-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-27 | — | — | WO | disclosed |