Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31209837 | 0.89 | CHRM1 (0.37) | CHRM2CHRM1CHRM3RET | |
| SCHEMBL31209754 | 0.89 | CHRM1 (0.37) | CHRM2CHRM1CHRM3RET | |
| SCHEMBL11530932 | 0.89 | CHRM1 (0.37) | CHRM2CHRM1CHRM3RET | |
| SCHEMBL3008190 | 0.79 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL92495 | 0.79 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL12832331 | 0.78 | NPC1 (0.39) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL19959235 | 0.78 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL1555763 | 0.78 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL14369076 | 0.78 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL78257 | 0.77 | SLC6A2 (0.33) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | claimed |
| EP-0614664-B1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | claimed |
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0614664-B1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5519024-A | CELL ADHESION INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0614664-A1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |