Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MATK | P42679 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | DNA2 | P51530 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540878 | 0.86 | GSK3B (0.44) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL9426359 | 0.82 | PIM3 (0.38) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL7499500 | 0.82 | PIM3 (0.36) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL10771039 | 0.81 | KDM4E (0.38) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10769201 | 0.81 | PIM3 (0.36) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL10508264 | 0.80 | CSNK2A1 (0.51) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL8937193 | 0.80 | KMT2A (0.50) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL10766998 | 0.79 | PIM3 (0.36) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL7011704 | 0.78 | PRKAB2 (0.34) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 | |
| SCHEMBL10769436 | 0.77 | KDM4E (0.44) | CSNK2A1CSNK2A2CSNK2BCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11060578-A | — | — | None | — | — | JP | disclosed |
| JP-5112554-A | — | — | None | — | — | JP | disclosed |
| EP-1187835-A4 | OPTICALLY ACTIVE QUINOLINE CARBOXYLIC ACID DERIVATIVES HAVING 7-PYRROLIDINE SUBSTITUTES CAUSING OPTICAL ACTIVITY AND A PROCESS FOR PREPARING THEREOF | DONG WHA PHARM IND CO LTD (KR) | 2003-01-29 | — | — | EP | disclosed |
| EP-1187835-A1 | OPTICALLY ACTIVE QUINOLINE CARBOXYLIC ACID DERIVATIVES HAVING 7-PYRROLIDINE SUBSTITUTES CAUSING OPTICAL ACTIVITY AND A PROCESS FOR PREPARING THEREOF | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000071541-A1 | OPTICALLY ACTIVE QUINOLINE CARBOXYLIC ACID DERIVATIVES HAVING 7-PYRROLIDINE SUBSTITUTES CAUSING OPTICAL ACTIVITY AND A PROCESS FOR PREPARING THEREOF | DONG WHA PHARM. IND. CO., LTD. (KR) | 2000-11-30 | — | — | WO | disclosed |
| EP-0561850-B1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | NAEJA PHARMACEUTICAL INC (CA) | 2000-07-12 | — | — | EP | disclosed |
| JP-H1160578-A | PYRIDONECARBOXYLIC ACID DERIVATIVE, ESTER THEREOF OR SALT THEREOF | DAINIPPON PHARMACEUT CO LTD | 1999-03-02 | — | — | JP | disclosed |
| EP-0559774-A1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5221676-A | 7-substituted quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1993-06-22 | — | — | US | disclosed |
| JP-H05112554-A | NEW QUINOLONECARBOXYLIC ACID DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1993-05-07 | — | — | JP | disclosed |
| EP-0242789-A2 | Novel quinoline derivates and processes for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0221463-A2 | Quinoline derivatives and processes for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-05-13 | — | — | EP | disclosed |