Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010011 | 0.91 | TOP2A (0.54) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL7007551 | 0.90 | TOP2A (0.52) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL5001698 | 0.88 | KCNH2 (0.44) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL7007583 | 0.86 | TOP2A (0.55) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL5001743 | 0.83 | TOP2A (0.45) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL4992199 | 0.82 | TOP2A (0.44) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL5001856 | 0.81 | TOP2A (0.44) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL5001786 | 0.81 | KCNH2 (0.49) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL7008776 | 0.81 | KDM4E (0.56) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL3720416 | 0.80 | TOP2A (0.58) | TOP2ATOP2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |