Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010192 | 0.91 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7012689 | 0.89 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7010948 | 0.86 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL7006879 | 0.85 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL7006386 | 0.84 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL7012087 | 0.83 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7010937 | 0.83 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL7010117 | 0.81 | EDNRA (0.47) | EDNRAEDNRB | |
| SCHEMBL7007652 | 0.81 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL8326131 | 0.80 | EDNRA (0.55) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601386-B1 | Sulphonamides | HOFFMANN LA ROCHE (CH) | 2003-02-05 | — | — | EP | claimed |
| EP-0601386-A1 | Sulphonamides | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | claimed |
| EP-0601386-B1 | Sulphonamides | HOFFMANN LA ROCHE (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0601386-A1 | Sulphonamides | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | disclosed |